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Diabetes can cause kidney disease in up to 40% of diabetics.103 High glucose levels can destroy the tiny blood vessels in the kidneys that filter waste, which may eventually lead to complete inability of the kidney to function.103 In fact, diabetic nephropathy is the most common cause of end-stage renal failure.86 Animal studies demonstrated that resveratrol diminishes severity of diabetic nephropathy, suggesting some benefit for humans with diabetes.21 |