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Pancreatic cancer is one of the most deadly cancers in humans, with only a 3% 5-year survival rate. Most pancreatic tumors cannot be surgically removed, and conventional chemotherapy and radiation cancer treatments don’t work very well either.218 Recent research may shed some light on why pancreatic tumors don’t respond well to treatment. It seems that they contain stem cells that appear to be resistant to chemotherapy. These cancer stem cells therefore continue to produce new cancer cells, and should be targeted in order to eradicate the tumor and prevent recurrence.218 In animal and lab studies, resveratrol was shown to stunt the growth and development of pancreatic tumors. It does so by inhibiting a gene that creates drug resistance and also by both inhibiting the regenerative activity of the cancer stem cells and causing them to die.218 Pancreatic cancer patients have high levels of formaldehyde in their blood and urine, a substance known to induce significant cancer pain. Research indicates that resveratrol neutralizes formaldehyde, suggesting that it can help reduce cancer pain and also limit formaldehyde’s cancer-stimulating effects.20
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